Stephen Novella stated the following:
In the end we have the same goals, design research that is carried out in such a way that it doesn’t matter what you believe, that the results will be valid despite the belief of the researcher...
Alex cheered this comment multiple times in the podcast. However I am not sure how realistic this is. Even clinical research trials in medicine show strong lab and experimenter effects, and standard psychology experiments do as well. I don't see how anyone can expect and hope that parapsychology experiments will ever be conducted without experimenter effects, since no other human subject science is able to do so. Sheep / goat performance differences for experimenters are the rule in parapsychology as in other fields of human-subject experimental science. Additionally, if the psi hypothesis is correct, then psi influence can work both for believers and disbelievers in psi phenomena to reveal or obscure psi effects.
This does not mean that every experiment by a sheep will demonstrate results, nor that every experiment by a goat will point at the null hypothesis. But there is a definite tendency for this in psi research, as well as clinical trials, standard psychology experiments, animal experiments, and other experiments with probabalistic results.
I'd also suggest additionally that if one's goal is primarily to "prove" psi or spiritual reality and "defeat" materialism once and for all one might well find oneself walking down the path tread by Susan Blackmore and Louie Savva, and ending up in the same place as they did. Because that kind of motivation does not seem to be correlated with fostering psi phenomena.